Urogenital Abnormalities Associated to Anorectal Malformations and Hirschsprung's Disease

Abstract

Introduction:�The aim of this study was to establishthe correlation between urinary pathologies and anorectal malformationsand Hirschsprung's disease andpresent their therapeutic particularities.

Means and Methods:�We retrospectively conducted a descriptive study at the Pediatric Surgery Department of the Queen Fabiola Children's University Hospital (HUDERF) in Brussels. We got a clearanceconsent fromthe ethical committee of our hospital. During one month, we retrieved files of children who consulted for anorectal malformations and Hirschsprung�s diseases from August 1, 2011 to June 31, 2024. We Included all patients presenting Hirschsprung�s disease and those with upper anorectal malformations. We excludedpatients who presented lower anorectal malformations. Clinical parameters that we recorded included: age, sex, type of imaging, type of urinary abnormalityand treatment.Data were analyzed with Microsoft Office Excel 2010 and SPSS 2.0 software.

Results:� We included 50 patients in our study; 16 cases of upper anorectal malformations and 34 cases of Hirschsprung's disease. For radiologic assessments, 30 patients underwent abdominal ultrasound (US) and urethrocystography wasdone in 8 patients. Sevencases of urologic anomalies were associated to anorectal malformations 43.8%. The different urinary abnormalitiesfound were multicystic kidney (3 cases), vesicoureteral reflux(2 cases) and renal dysplasia (2 cases). Four cases of urologic malformations were associated toHirschsprung's diseaseat least 11.8% (2 cases of megaureter and2 cases of hydronephrosis). The conservative treatment has been practiced associated to antibiotic prophylaxis in10 cases.

Conclusion: This study is showing that urogenital abnormalitiesaremostly associated to anorectal malformations than Hirschsprung's disease. In many casesthe treatment is conservative