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\title{Adrenal Myelolipoma : A Rare Case of the Incidentaloma : About One Case}
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\date{\small \em Received: 1 January 1970 Accepted: 1 January 1970 Published: 1 January 1970}

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\begin{abstract}
        


Background: Adrenal myelolipoma is a rare, benign, non-functioning tumor of the adrenal gland. Which is why it is often asymptomatic, but it may be complicated by pain or retroperitoneal hemorrhage. Medical imaging is key to the diagnosis by highlighting its fatty component, non present in other adrenal incidentalomas. Surgery is indicated when there is a large or Complicated Myelolipoma. We report the case of a large symptomatic adrenal myelolipoma discovered in a 50 year old woman.Case report: We describe a case of an 8cm non-functional, and heterogenous right adrenal myelolipoma discovered on a routine computed tomography (CT) scan evaluation for cervical cancer in a 50 years old woman.

\end{abstract}


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{{\textit{CrossRef DOI of original article:}} \underline{}}
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\section[{I. INTRODUCTION}]{I. INTRODUCTION}\par
Adrenal myelolipoma is a rare, benign, nonfunctioning tumor of the adrenal gland. Which is often asymptomatic, but it may be complicated by pain or retroperitoneal hemorrhage. Medical imaging is key to the diagnosis by highlighting its fatty component, non present in adrenal incidentalomas. Surgery is indicated when there is a large or Complicated Myelolipoma. We report the case of a large symptomatic adrenal myelolipoma discovered in a 50 year old woman. 
\section[{II.}]{II.} 
\section[{OBSERVATION}]{OBSERVATION}\par
The patient was a 50 year-old married woman, G8P5, diabetic, with a history of cervical cancer, was referred to our institution for an adrenal mass found on a Ct scan performed to assess her cervical cancer. Ct scan revealed a well-defined 8 cm Heterogenous mass of the right adrenal gland. The patient exhibited no clinical signs of adrenal dysfunction : the clinical evaluation was normal.   
\section[{DISCUSSION}]{DISCUSSION}\par
Once considered an autopsy curiosity, adrenal myelolipoma is now increasingly diagnosed with the frequent use of modern imaging methods. In a recent meta-analysis, fewer than 100 cases were reported(1). The real incidence of adrenal myelolipoma is difficult to determine because of its rarity and its mostly asymptomatic character(2). It is estimated to be between 0.08 and 0.2\% in old autopsy series(3).\par
It is most often discovered in the fifth decade of life (extremes from 17 to 93 years) with a slight male predominance. Adrenal myelolipoma is most often unilateral, and is frequently associated with obesity, high blood pressure (HTA), endocrine disorders or various tumor diseases (3) (4).\par
The origin of these tumors remains poorly understood. The metaplastic theory is the most widely accepted: the adrenal myelolipoma would derive from reticular cells of the adrenal cortical framework in response to an infection, to necrotic lesions of the adrenal gland or to chronic stress (4).\par
Adrenal myelolipoma is a non-secreting tumor that does not cause any adrenal hormonal dysfunction. It is most often asymptomatic(5).\par
It may manifest itself by non-specific symptoms consisting of nonspecific abdominal pain secondary to the mass effect in the case of large tumors, or intratumoral hemorrhagic and necrotic phenomena 2'. high blood pressure may be observed in case of compression of a renal artery.\par
Rarely, due to tumor rupture, patients may present with acute back pain, associated with a state of hypovolemic shock secondary to retroperitoneal hemorrhage. This is a serious complication that can be life-threatening and require emergency surgery (6).\par
Imaging studies are most often helpful in making the diagnosis and differentiating adrenal myelolipoma from other adrenal incidentalomas by demonstrating its fatty component 2".\par
Ultrasound typically shows a markedly hyperechoic adrenal mass of solid nature. CT scan is the gold standard for the diagnosis. It usually shows a well-limited adrenal formation, which may be septate or contain fine calcifications that displace the healthy adrenal parenchyma. It allows above all to detect the fatty contingent of the tumor characterized by a negative density of -50 to -100 UH (7).\par
Sometimes, the diagnosis can be more challenging when there are some hemorrhagic changes or preponderance of the myeloid component masking the "fatty" character; the adrenal myelolipoma may then appear hypoechoic on ultrasound and hyperdense taking the contrast medium on CT. This appearance may be confused with a pheochromocytoma or a non-secreting adrenal carcinoma or even a renal angiomyolipoma. In these situations, magnetic resonance imaging (MRI) can be useful and allow a better tissue characterization of the components of the adrenal myelolipoma by demonstrating a clear hypersignal on T1-weighted sequences and a T2 signal attenuation for the fatty component as well as a hyposignal in T1 and an intermediate signal in T2 for the hematopoietic component.\par
In case of persistent diagnostic doubt, particularly in patients with a history of extrasensory neoplasia, or in bilateral forms, fine needle aspiration guided by ultrasound or ct scan with cytological study is justified and can sometimes avoid unnecessary surgery.\par
Adrenalectomy is the primary treatment and may be indicated in the following settings: painful forms, complicated forms (hemorrhage, compression), doubt on a malignant component. With the progress made in laparoscopic surgery, surgical excision is increasingly recommended by this route(8).\par
Management of asymptomatic adrenal myelolipoma, is controversial. They are most often simply monitored by imaging. However, any increase in volume during follow-up will warrant surgical removal, given the risk of haemorrhagic complications.\par
A few authors systematically indicate surgical removal from the outset, while others reserve this attitude for large tumors (8).\par
London Journal of Medical and Health Research 
\section[{35}]{35}\par
Adrenal Myelolipoma : A Rare Case of the Incidentaloma : About One Case\par
Regular monitoring, based mainly on CT, is necessary because of the possibility of development of lateral adrenal myelolipoma.\par
The prognosis after surgical treatment is good, with recurrence-free follow-ups of up to 12 years. 
\section[{IV. CONCLUSION}]{IV. CONCLUSION}\par
Adrenal myelolipoma is a benign tumor, rare and often asymptomatic of incidental discovery.\par
Imaging usually allows the diagnosis to be evoked. The complicated, sympathetic or voluminous nature of the adrenal myelolipoma should indicate surgical removal with anatomopathological confirmation. otherwise, surveillance by imaging is recommended. 
\section[{London Journal of Medical and Health Research}]{London Journal of Medical and Health Research}\begin{figure}[htbp]
\noindent\textbf{1}\includegraphics[]{image-2.png}
\caption{\label{fig_0}Figure 1 :}\end{figure}
 \begin{figure}[htbp]
\noindent\textbf{2}\includegraphics[]{image-3.png}
\caption{\label{fig_1}Figure 2 :}\end{figure}
 			\label{foot_0}\footnote{\label{foot_0} Adrenal Myelolipoma : A Rare Case of the Incidentaloma : About One Case © 2023 Great ] Britain Journals Press} 		 		\backmatter  			  				\begin{bibitemlist}{1}

\end{bibitemlist}
 			 		 	 
\end{document}
