Effectiveness and Safety of Treatment of Double Chin with Combined Enzymatic Therapy

Authors

  • Dr. Jorge Lopez Berroa

DOI:

https://doi.org/10.34257/LJMHR225763UK

Keywords:

collagenase, combined enzymatic treatment, double chin, hyaluronic acid, lipase, lyase

Abstract

Cellulite is a common aesthetic concern that may significantly impact on individuals’ self-image and quality of life. Despite being a non-threatening condition, it may have a negative effect on the psychological well-being of affected individuals. This condition is multifactorial and involves several physiopathology pathways. The role of enzymes in the management of cellulite is a novel approach, particularly lipase and collagenase, which play key roles in adipocyte size reduction and collagen degradation, respectively. The potential of high-molecular-weight hyaluronic acid to promote tissue repair and regeneration is also highlighted. Our case report describes the effectiveness of an association of recombinant enzymes and high-molecular-weight hyaluronic acid by reducing cellulite manifestations in a patient, with a history of multiple unsuccessful treatments, showing visible improvements from the initial treatment session. The importance of understanding the complex physiopathology of cellulite and choosing a targeted approach is emphasized.

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Published

2026-02-28

How to Cite

Effectiveness and Safety of Treatment of Double Chin with Combined Enzymatic Therapy. (2026). London Journal of Medical and Health Research, 26(2), 27-34. https://doi.org/10.34257/LJMHR225763UK